Nystatin cream USP 100,000 units per gram is a topical antifungal medication used to treat skin infections caused by the fungus Candida. It is effective against various types of Candida, including Candida albicans, the most common cause of yeast infections.
Nystatin cream works by binding to the ergosterol in the fungal cell membrane, leading to increased permeability and leakage of intracellular contents. This results in cell death and inhibits fungal growth.
Nystatin cream is indicated for the treatment of the following skin infections caused by Candida:
For Oral Thrush:
For Diaper Rash:
For Vulvovaginal Candidiasis:
For Interdigital Candidiasis:
For Paronychia:
Nystatin cream offers several benefits, including:
Pros:
Cons:
Table 1: Common Candida Species Affected by Nystatin Cream
Species | Percentage of Infections |
---|---|
Candida albicans | 80-90% |
Candida glabrata | 10-15% |
Candida parapsilosis | 1-5% |
Candida krusei |
Table 2: Dosage and Duration of Treatment for Different Indications
Indication | Dosage | Duration of Treatment |
---|---|---|
Oral thrush | 4 times daily | 7-14 days |
Diaper rash | 2-3 times daily | Up to 14 days |
Vulvovaginal candidiasis | Twice daily | 7-14 days |
Interdigital candidiasis | 2-3 times daily | Up to 14 days |
Paronychia | Twice daily | Up to 14 days |
Table 3: Common Side Effects of Nystatin Cream
Side Effect | Frequency |
---|---|
Skin irritation | 1-10% |
Burning sensation |
1. How long does it take for nystatin cream to work?
It typically takes 7-14 days of regular application for nystatin cream to effectively treat fungal infections.
2. How often should I apply nystatin cream?
The frequency of application depends on the indication being treated. Consult your healthcare provider for specific instructions.
3. Is nystatin cream safe for pregnant women?
Yes, nystatin cream is generally considered safe to use during pregnancy.
4. Can I use nystatin cream on my face?
Nystatin cream is not recommended for use on the face without consulting a healthcare provider.
5. What should I do if I experience side effects from nystatin cream?
Discontinue use and contact your healthcare provider if you experience significant skin irritation or allergic reaction.
6. Can nystatin cream be used to treat nail infections?
Yes, nystatin cream can be used to treat paronychia, a type of nail infection. However, it may not be effective against all types of nail infections.
7. How should I store nystatin cream?
Store nystatin cream at room temperature (15-30°C) in a cool, dry place.
8. What is the difference between nystatin cream and clotrimazole cream?
Both nystatin and clotrimazole are antifungal medications. Nystatin is effective against Candida, while clotrimazole is effective against a wider range of fungi, including Candida and dermatophytes.
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